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The cervix, situated at the lower end of the uterus, serves as the link between the uterus and the vagina. Cervical cancer, which impacts the cells in this area, is predominantly triggered by the Human Papillomavirus (HPV). In India, cervical cancer accounts for about 16.5% of all cancer cases, making it the second most prevalent cancer among women following breast cancer. Fortunately, cervical cancer is preventable through precautionary measures and vaccination. While unprotected sexual activity with multiple partners is a primary risk factor, it's crucial to understand that not every individual infected with HPV will develop cervical cancer; specifically, only HPV-16 and HPV-18 strains are implicated. Other potential contributors to cervical cancer may include smoking, multiple pregnancies, and early initiation of sexual activity. It's important to note that HPV can affect both men and women, particularly if either engages in unprotected sex with multiple partners.
The cost of cervical Cancer Vaccine in Noida India may vary from Rs 3927/ to Rs 10,850.
Starting Cost | ₹3,927 |
Average Cost | ₹5,500 |
Maximum Cost | ₹10,850 |
Cervical Cancer is the 4th most common cancer in women globally and the only one that is preventable. The HPV vaccine plays a pivotal role in averting various cancer types, such as cervical, anal, and oropharyngeal cancers. Additionally, it serves as a protective shield against specific virus strains associated with women's infertility.
While reports of Poonam Pandey's fake death from cervical cancer may grab attention, it's crucial to recognize the gravity of the actual situation: a woman dies from this disease every 2 minutes. In response, the government has launched a groundbreaking initiative to provide free Cervical Cancer Vaccines for girls aged 9 to 14. This proactive step not only underscores the urgency of preventive measures but also reflects the government's commitment to reducing the impact of this formidable health challenge and promoting a healthier future for the nation.
Cervical cancer originates from the growth of cells in the cervix, the lower part of the uterus connected to the vagina. Most cases of cervical cancer are linked to various strains of the human papillomavirus (HPV), a common infection transmitted through sexual contact. While the body's immune system can often combat HPV upon exposure, in a small percentage of individuals, the virus persists for an extended period, contributing to the development of cancerous cervical cells.
To minimize the risk of cervical cancer, individuals are advised to undergo screening tests and receive a vaccine designed to protect against HPV infection. In cases where cervical cancer is diagnosed, initial treatment typically involves surgery to remove the cancer. Additional treatment options may include medications to eliminate cancer cells, such as chemotherapy and targeted therapy. Radiation therapy, utilizing potent energy beams, may also be employed, sometimes in combination with low-dose chemotherapy.
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Cervical cancer may not initially exhibit noticeable symptoms. However, as the cancer progresses, individuals might experience signs such as:
Cervical cancer initiates when the DNA of healthy cells in the cervix undergoes alterations. DNA, functioning as a cell's instructional manual, directs its activities. These alterations prompt rapid cell multiplication, enabling them to persist beyond their natural life cycle, resulting in an excess of cells. This surplus might form a mass known as a tumor, capable of infiltrating and damaging surrounding healthy tissues. Over time, these cells can detach and metastasize to other areas of the body.
The predominant cause of cervical cancer is the Human Papillomavirus (HPV), a common virus transmitted through sexual contact. While many individuals naturally clear the virus without complications, some may experience changes in cells that elevate the risk of cancer.
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Cervical cancer manifests in various types, primarily categorized based on the cell where the cancer originates. Squamous cell carcinoma, the most prevalent type, originates in thin, flat squamous cells lining the cervix's outer part. Adenocarcinoma, on the other hand, begins in column-shaped gland cells lining the cervical canal. Occasionally, both cell types may be involved, and more rarely, cancer may develop in other cervical cells.
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Risk factors associated with cervical cancer comprise:
Understanding these risk factors is crucial for implementing preventive measures and promoting early detection in cervical cancer screenings.
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HPV, or human papillomavirus, constitutes a group of viruses transmitted through skin-to-skin sexual contact, encompassing anal, vaginal, and at times, oral sex. Notably, HPV transmission can occur even years after sexual activity has ceased. Specific strains of HPV are linked to cervical cancer.
One of the most widely used vaccines against cervical cancer is Gardasil. It safeguards against two HPV strains responsible for 70% of cervical cancers. To fully benefit from this vaccine, it should be administered before exposure to any HPV strains covered by it. The recommended age for Gardasil vaccination is 11-12 years, with additional recommendations for girls and women aged 13-26 who have not yet received or completed the vaccination series. The vaccine's efficacy tends to be higher at younger ages. Ideally, females should receive the cervical cancer vaccine before initiating sexual activity and potential HPV exposure. However, sexually active females can still benefit from the vaccine, though to a lesser extent.
The CDC advises that individuals aged 11 to 12 should receive two doses of the HPV vaccine, administered 6 to 12 months apart.
The initial dose is typically given at ages 11 to 12, although vaccination can commence at age 9. If the first dose is administered before the 15th birthday, only two doses are necessary.
For those who begin the series later, between ages 15 and 26, three doses of the HPV vaccine are required.
Children aged 9 to 14 who have received two doses less than 5 months apart will require a third dose. Additionally, individuals aged 9 to 26 with weakened immune systems should receive three doses.
Vaccination is not recommended for individuals older than 26 years, although some adults aged 27 to 45 who have not been vaccinated may opt to receive the HPV vaccine after consulting with their doctor regarding their risk of new HPV infections and the potential benefits of vaccination. However, HPV vaccination in this age group offers reduced benefits due to higher rates of HPV exposure.
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Have experienced a life-threatening allergic reaction to any component of an HPV vaccine or to a prior dose of the vaccine.
Are allergic to yeast (specifically applicable to Gardasil and Gardasil 9).
It is safe for children with mild illnesses, such as a low-grade fever below 101 degrees Fahrenheit, a cold, runny nose, or cough, to receive HPV vaccines. However, individuals with moderate or severe illnesses should postpone vaccination until they have recovered.
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There are three HPV vaccines—Gardasil 9 (9vHPV), Gardasil (4vHPV), and Cervarix (2vHPV)—all of which have been approved by the U.S. Food and Drug Administration (FDA). Each of these vaccines guards against HPV types 16 and 18, the main culprits behind most HPV-related cancers.
As of late 2016, Gardasil-9 (9vHPV) is the exclusive distribution in the United States. This particular vaccine provides protection against nine HPV types (6, 11, 16, 18, 31, 33, 45, 52, and 58).
The vaccination schedule spans 6 to 24 months, with two injections administered. Presently, the vaccine's effectiveness extends to 8-10 years, possibly even longer, though ongoing research investigates long-term efficacy and the necessity for booster doses. Cervical cancer vaccines are generally safe, with minimal side effects such as pain, swelling, soreness, or redness at the injection site. Occasionally, dizziness or fainting may occur post-injection, but this risk can be mitigated by remaining seated for about 15 minutes afterward.
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Cervical cancer vaccines operate similarly to other immunizations that shield against viral infections. They prompt the body to produce antibodies, which, upon future encounters with HPV, bind to the virus, preventing it from infecting cells.
The efficacy of HPV vaccination is remarkably high, with the potential to prevent over 90% of HPV-related cancers.
Since the recommendation for HPV vaccination in 2006, infections caused by HPV types responsible for the majority of HPV-related cancers and genital warts have seen an 88% decline among adolescent girls and an 81% decrease among young adult women. There's also been a noticeable decrease in cases of genital warts among teens and young adults, as well as a reduction in precancerous cervical lesions in young women.
The protective effects of HPV vaccines have demonstrated long-lasting efficacy. Individuals who received HPV vaccines were monitored for at least 12 years, during which their immunity against HPV remained robust, showing no signs of waning over time.
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Similar to any medication, vaccines may have side effects. Many individuals who receive the HPV vaccine experience no adverse effects at all. For those who do, the side effects are typically mild and include:
To mitigate the risk of fainting and potential injuries, adolescents should remain seated or lying down during vaccination and for 15 minutes after receiving the shot.
Although rare, severe allergic reactions (anaphylaxis) may occur following vaccination. Individuals with severe allergies to any component of the vaccine should avoid receiving it.
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HPV vaccines may be available at doctor's offices, community health clinics, school-based health centers, and health departments. If your healthcare provider does not offer the HPV vaccine, you can request a referral to a suitable provider.
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To mitigate the risk of cervical cancer, individuals are advised to consider preventive measures:
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